OBDN

OBSIDIAN PEPTIDES

The Recomp Catalyst

5-Amino-1MQ

Inhibits NNMT → shifts methyl/NAD metabolism; proposed increase in adipocyte energy expenditure

The Fat Mobilizer

AOD-9604

Lipolysis signaling via GH fragment without GH-mediated hyperglycemia

The Neural Shield

ARA-290

Innate-repair-receptor activation → neurovascular protection

The Master Healer

BPC-157

Promotes angiogenesis, accelerates tissue regeneration, and protects gut integrity through growth-factor modulation

Benefits
  • Accelerated wound and tendon repair
  • Gut healing and protection
  • Vascular and nerve regeneration
  • Anti-inflammatory effects

The gold standard for tissue repair across gut, musculoskeletal, vascular, and neural systems

The Cartilage Signal

Cartalax

Bioregulatory gene modulation in chondrocytes

The Long-Acting Amplifier

CJC-1295

DAC-modified GHRH analog → extended half-life, sustained GH release amplification

The Sleep Regulator

DSIP

Delta-sleep inducing peptide → circadian rhythm modulation, stress-hormone regulation

The Circadian Optimizer

Epitalon

Proposed epigenetic regulation of circadian rhythms; melatonin modulation

The Remodeler

GHK-Cu

Copper-dependent collagen/elastin synthesis, MMP inhibition

Benefits
  • Dermal renewal and skin quality
  • Connective-tissue strength
  • Anti-inflammatory effects

Anti-aging crossover with tissue repair benefits

The Anabolic Master

hGH

Direct GH supplementation → IGF-1 elevation, protein synthesis, lipolysis, tissue regeneration

Benefits
  • Enhanced muscle growth and recovery
  • Fat loss and body recomposition
  • Improved skin and connective tissue
  • Bone density support

Requires careful dosing and monitoring; may suppress natural GH production

The Recovery Enhancer

Ipamorelin

Selective ghrelin receptor agonist → GH pulse without cortisol/prolactin elevation

The Inflammation Brake

KPV

α-MSH fragment → NF-κB and cytokine suppression

Benefits
  • Calms inflammatory microenvironment
  • Supports epithelial recovery
  • Post-injury tissue repair

Potent anti-inflammatory for gut and systemic inflammation

The Transporter

L-Carnitine

Carnitine shuttle transports long-chain fatty acids into mitochondria for beta-oxidation

The Metabolic Optimizer

MOTS-C

Stress-responsive peptide that translocates to nucleus; up-regulates AMPK/FOXO programs

Benefits
  • Enhanced glucose and fatty-acid handling
  • Improved exercise adaptation
  • Metabolic flexibility enhancement

Weight recomposition support

The most fundamental molecule in cellular metabolism.

NAD+

100-500mg

NAD+ is the prerequisite that makes all other healing possible. It transforms cellular metabolism from survival mode to repair mode.

Every cell requires NAD+
  • Transfer electrons for ATP production
  • Power DNA repair
  • Regulate gene expression
  • Maintain cellular stress responses
Metabolic Function

Acting as a crucial electron carrier that powers the cell's energy-producing machinery.

Signaling Function

Serving as a master regulator of cellular health by supporting enzymes like sirtuins and PARPs.

The Neuroplasticity Catalyst

P21

CREB phosphorylation → BDNF transcription, dendritic spine growth, synaptic plasticity

The Cognitive Shield

Pinealon

CNS trophic claims; proposed oligopeptide regulatory effects on brain tissue

The Triple Threat

Retatrutide

Triple GLP-1 (satiety), GIP (insulinotropic/central effects), glucagon (lipolysis/EE) agonist

Benefits
  • Aggressive fat loss
  • Enhanced energy expenditure
  • Improved metabolic markers
  • Requires resistance training 3×/week

Most aggressive metabolic intervention; must be paired with consistent resistance training

The Appetite Regulator

Semaglutide

GLP-1R agonism with albumin-binding for extended half-life

The Cognitive Enhancer

Semax

ACTH(4-10) analog → BDNF upregulation, D1/D2 receptor density increase, enkephalinase inhibition

Benefits
  • Enhanced focus and mental clarity
  • Improved memory consolidation
  • Neuroprotective effects
  • Stress resilience and anxiety reduction

Powerful nootropic for CNS optimization, cognitive function, and stress response modulation

The Anxiolytic

Selank

Tuftsin analog → GABAergic and serotonergic modulation, enkephalin stabilization

Benefits
  • Anxiety reduction without sedation
  • Improved stress tolerance
  • Enhanced mood stability
  • Immune modulation

CNS, emotional regulation, and immune system support without sedative effects

The Natural Secretagogue

Sermorelin

GHRH(1-29) analog → stimulates natural pulsatile GH release from pituitary

The Mitochondrial Guardian

SS-31

Binds cardiolipin in inner mitochondrial membrane → stabilizes cristae, improves electron transport efficiency

Benefits
  • Reduced post-exertional malaise
  • Improved HRV and orthostatic tolerance
  • Enhanced mitochondrial function
  • Steadier work output

Cardiolipin stabilization is dose-dependent early; tapering reduces cost while keeping membrane effects

The Mobilizer

TB-500

Actin polymerization → cell migration and angiogenesis

The Fat Reducer

Tesamorelin

GHRH analog → pulsatile GH secretion, targeting visceral adipose tissue (VAT) reduction

Benefits
  • Visceral fat reduction
  • Improved body composition
  • Enhanced metabolic markers
  • Lipid profile improvement

Targets growth hormone axis, metabolic function, and body composition optimization

The Dual Agonist

Tirzepatide

GLP-1 satiety/gastric delay + GIP insulinotropic/central effects

The Inflammation Modulator

VIP

Vasoactive Intestinal Peptide → immunomodulation, anti-inflammatory cytokine release, circadian regulation